Brief introduction of CHAPS CAS 75621-03-3
Chemical name: 3-((3-Cholamidopropyl)dimethylammonium)-1-propanesulfonate
CAS No.：75621-03-3
Synonyms: CHAPS
Molecular Formula: C32H58N2O7S
Molecuar Weight: 614.88
EINECS: 616-246-2
Properties of CHAPS CAS 75621-03-3
CHAPS(0.5%)isabletostabilizecomplexesbetweenDNAandDNA-bindingfactorssuchasAP-1,SPI,GATA-1andα-regulatedfactorISGF3,Chemicalbookandretainstheirbiochemicalactivity.CHAPScanpreventdissociationofmononucleosomesdilutedtosub-nanomolarconcentrations.
Specification of CHAPS CAS 75621-03-3
Item |
Standard |
Appearance |
White to off-white crystalline powder |
Particle size |
95% pass through 80 mesh |
Assay, % |
≥98.0 |
Melting point, ℃ |
156-158 |
Application of CHAPS CAS 75621-03-3
CHAPS is a non-denaturing zwitterionic detergent used in membrane biochemistry. It can be used to solubilize membrane proteins and break protein-protein interactions. CHAPS has a low micelle molecular weight (6,150) and a high critical micelle concentration (6-10 mM), so it can be removed from the sample by dialysis. Chemicalbook It is also suitable for solubilizing proteins in isoelectric focusing and two-dimensional electrophoresis. CHAPS is often used for non-denaturing (no urea) isoelectric focusing, and it has been found to have excellent resolution for certain subcellular preparations and vegetable proteins. Usually a concentration between 2-4% (w/v) is used for isoelectric focusing gels.
Packing, Delivery and Storage of CHAPS CAS 75621-03-3
Package: 25kg /bag or fiber drum, or as per customer request.
Storage conditions: store in a cool and dry place.
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