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Estriol CAS 50-27-1

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Product Information

Product name               Estriol
Synonyms                   1,3,5-Estratriene-3beta,16-alpha,17-beta-triol
CAS No.                      50-27-1
EINECS                       200-022-2
M.F.                           C18H24O3
M.W.                          288.38

Physical Properties
White crystalline powder. Poorly soluble in water, slightly soluble in ethanol, ethyl ether, chloroform, dioxane and vegetable oils, soluble in pyridine and hydroxide alkaline solution.
Density                      1.255g/cm3
Boiling Point               469℃ at 760 mm Hg
Flashing Point             220.8℃
Refractive Index         58°(C=0.4, Dioxane)

Specification
Items                       Specification
Appearance               White-like Crystalline powder
Melting range            165℃ ~ 169℃
Loss on drying           ≤0.5%
Optical rotation          +54°~ +62°
Residue on Ignition    ≤0.1%
Assay by HPLC           97.0 ~ 102.0%

Applications
1. Used for cervicitis, especially for menopausal syndrome, senile vaginitis.
2. It can be used as mid-term abortion and induced abortion drugs.
3. Used for prostate hypertrophy, prostate cancer.
4. There is a rapid increase in the role of peripheral white blood cells, generally in the 1 to 3 days after the entry into force, but the role of maintaining a shorter time. On chemotherapy or radiotherapy-induced leukopenia effective.
5. It can reduce vascular permeability and brittleness, can be used for a variety of bleeding treatment, for menorrhagia, tonsil or hysterectomy, have a rapid hemostasis.

Packaging
1kg per Aluminum foil bag, 5kg per Aluminum tin or as per customer’s requirements

Storage
Store in under normal temperature cool place. Keep container tightly closed in a dry and well-ventilated place. After opening the sealed packaging barrels must carefully again and stand to avoid leakage.
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