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Indomethacin is a white or slightly yellow crystalline powder. Melting point 158-162°C. It is soluble in acetone, slightly soluble in ethanol, chloroform, ether, and almost insoluble in water. Tasteless and almost odorless.
Specification
Melting point 155-162°C
Storage conditions Store at RT
Solubility ethanol:50mg/mL,clear,yellow-green
Related substances(TLC) ≤0.5%
Loss on drying ≤0.5%
Sulphated ash ≤0.1%
Heavy metals ≤20ppm
Related solvent ≤0.5%
Content 98.5-100.5%
Application
Cyclooxygenase (COX) inhibitor, which selectively inhibits COX-1; blocks the biosynthesis of prostatic cord.
It has obvious anti-inflammatory and antipyretic effects in medicine. It is mainly used for rheumatic complication, ankylosing spondylitis, osteoarthritis, etc. that are not easily tolerated or not effective to salicylic acid drugs.
25 kg/fiber drum