Brief introduction of Olaparib CAS 763113-22-0
Chemical name: Olaparib
CAS: 763113-22-0
Synonyms: 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]piperazin
Molecular Formula: C24H23FN4O3
Molecuar Weight: 434.46
EINECS: 642-941-5
Properties of Methyl 2-nitrobenzoate CAS 606-27-9
Melting point: 133-135°C(lit.) Boiling point: 462.4±40.0°C(Predicted) Density: 1.439±0.06gChemicalbook/cm3(Predicted) Storage conditions Keepindarkplace, Inertatmosphere, 2-8°C
Specification of Methyl 2-nitrobenzoate CAS 606-27-9
Item |
Standard |
Appearance |
White crystalline powder |
Content, wt% |
≥98.00 |
Water, w% |
1.0 max |
Application of Methyl 2-nitrobenzoate CAS 606-27-9
Olaparib is a new type of poly ADP ribose polymerase (PARP) inhibitor, including PARP1, PARP2, and PARP3. PARP mediates a DNA repair mechanism that plays an important role in DNA damage repair and cell apoptosis. Therefore, Olapani Chemicalbook specifically acts on the DNA damage repair mechanism of targeted cells by attacking cancer cells carrying BRCA1 and BRCA2 mutations. The key loopholes in the system play a role and can be used for the maintenance treatment of patients with breast cancer susceptibility gene (BRCA) mutations and recurrent severe ovarian cancer who are sensitive to platinum drugs.
Packing, Delivery and Storage of Methyl 2-nitrobenzoate CAS 606-27-9
Package: 25kg /drum, or as per customer request.
Storage conditions: store in a cool and dry place.
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